Astrologaster follows the whimsical misadventures of Simon Forman, an astrologer and self-proclaimed doctor in 1592 London amidst a devastating plague. As actual physicians abandon the city in terror, Simon takes it upon himself to heal the sick, despite his dubious skills in both medicine and astrology. With the epidemic dissipating, his troubles escalate as genuine doctors return, eager to expose his charlatan ways. In a bid to secure his legitimacy, Simon seeks to win over patients by gathering glowing letters of recommendation, each one bringing him closer to realizing his dream of obtaining a medical license. The narrative is interspersed with humorous dialogue reminiscent of classic sitcoms, brought to life by a talented ensemble of voice actors, creating a light-hearted yet absurd commentary on trust and expertise in a time of crisis.